Games like The Binding of Isaac: Four Souls

Looking for games like The Binding of Isaac: Four Souls? It's a strategy game with real decisions on every turn — built on asymmetric powers that make your side play unlike any other and deals, bluffs, and shifting alliances around the table. This page rounds up 12 of the closest alternatives, scored on mechanical overlap with the original (45%), complexity match (35%), and player-count fit (20%), then weighted by BoardGameGeek community ratings so every pick is one players genuinely rate. The strongest matches come first; the further down you go, the more a game trades exact overlap for a fresh take on the same core appeal.